Corneal Collagen Cross-Linking (C3R) with Riboflavin

Corneal Collagen Cross-Linking with Riboflavin (also abbreviated as C3R) is a non-invasive corneal treatment shown to slow the progression of keratoconus. It does so by increasing the strength of corneal tissue. Undergoing C3R in the early stages may help stabilize vision. While the treatment will not correct vision or eliminate the need for glasses and/or contact lenses, it can help maintain the current level of vision and is meant to prevent vision from worsening. It can also help those that cannot wear contact lenses to more easily fit into them.

Corneal Collagen Cross-linking with Riboflavin (C3R) has been demonstrated in Europe to strengthen a weakened corneal structure. This simple, well-tolerated procedure begins with the application of riboflavin (vitamin B2) drops on the cornea which are then activated with a mild UV (Ultraviolet) light. The interaction of Riboflavin and UV light causes the links within the cornea to re-bond and strengthen over time. These natural links are responsible for maintaining stability of the corneal structure and preventing the cornea from irregular bulging and excessive steepening which leads to advanced Keratoconus.

Corneal Collagen Crosslinking, which has demonstrated long-term stability, is a less invasive treatment as compared to corneal transplants.